The film opens with a bourgeois couple, Paul and Hélène, he a totally self-absorbed business man, and she the working wife who takes care of everything else. They are dashing off somewhere when a woman runs down the middle of the road towards their car screaming for them to open the door. Paul promptly locks it, and the three men chasing the woman proceed to beat her mercilessly, leaving a bloodstain on the car's windscreen and her in the gutter. Hélène wants to get out and help, but Paul's having none of it, his priority being to drive to the nearest carwash.
Hélène is haunted by what has happened and finds out to which hospital the woman was taken, where she pretends to be a friend. The woman, Noémie (aka Malika) is in a coma, suffers a cardiac arrest and the medical staff can't say whether she will be partially paralysed. Hélène talks the hospital staff into allowing her to stay at the hospital, where she devotes herself to helping Noémie recover.
Meanwhile, things aren't going well for Paul. Unable to contact Hélène, and hopeless at doing anything for himself in the apartment, his life is falling apart. Add to this his son, Fabrice, who's seriously upsetting two girlfriends, and Paul's life is becoming hell.